Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring Matt Kirshen, Andy Wood, Jesse Case and guests.

Episodes

Episode 566 with Amy Silverberg!

May 7, 2025

Comedian, writer and author of upcoming novel “First Time, Long Time” Amy Silverberg (@amysilverberg) joins the gang to talk about Andy’s Irish landscape spotting! The optimal amount of bra bounce! Andy’s Iberian adventures! Lions biting gladiators! Men fighting gorillas! And which glasses to wear to avoid the fight yourself!

In the Patreon bonus we talk about lucid dreaming and a new state of consciousness.

Please go and see Matt Jul 16 in Columbus OH, Jul 31 in Hartford CT, or Oct 12 in Virginia Beach VA.

And Andy’s band on May 31 at Coyote Run Studio in Joshua Tree.

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Episode 565 with Tony Camin!

May 2, 2025

Great stand-up and co-creator of the Marijuana-Logues Tony Camin (@tony.camin) joins Jesse and Matt to talk about crows’ geometry skills! Tony helping one of the fathers of decision analysis! Why seals don’t drown! Unlikely animal friends! And whether your month of conception shapes your body!

Tony’s new album, An Ass Pocket of Whimsy will come out on Stand-Up! Records and you can find him at tonycamin.com.

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Episode 564 with Samantha Hale!

April 26, 2025

Comedian and Horror Nerd Samantha Hale (@thesamanthahale) joins Jesse and Matt to talk about: A layer of life deep below us! The not actually back from extinction dire wolves! The Earth’s mysterious pulsations! and Reagan’s obsession with the Titanic!

In the Patreon bonus we talk about bending sounds.

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Episode 563 Live from Perth with Wil Anderson and Robyn Perkins!

April 17, 2025

Friend of the show Wil Anderson (@officialwilanderson) joins Matt live in Perth along with marine biologist-turned-comedian Robyn Perkins (@robynhperkins) to talk all things coral, nudibranchs, poisonous sea creatures and surprising things to do with dry ice and mouths.

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Episode 562 with Shawn Carlow!

March 31, 2025

Writer/comedian Shawn Carlow (@shawncarlow) joins Jesse, Andy and Matt to talk about his new book People of the Titanic: 30 Tales of Extra-Doomed Souls Who Sailed on The Ship of Dreams, mouse-to-mouse resuscitation, what your poop schedule says about your health and physicists creating a supersolid out of light.

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Episode 561 Live from Perth with Ross Noble, Kirsty Webeck and Paul Savage!

March 18, 2025

Live from Perth, Matt is joined by Ross Noble, Kirsty Webeck and Paul Savage to talk about if you can cook a chicken by throwing ice cubes at it, dolphins communicating with pee streams, dormant volcanoes that aren’t that dormant and astronauts’ eyesight.

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Episode 560 with James P. Connolly!

March 6, 2025

Comedian James P. Connolly (@jamespconnolly) joins Andy, Jesse and Matt on location from the SLO Comedy Festival to talk about centaurs and minotaurs, plum grenades, forcing comedy on bar patrons, the asteroid that was at one point maybe going to hit us, the return of measles, Jesse's update on the state of Nashville, overly clean living conditions in space and microscopic obelisks in your gut.

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Episode 559 with Aidan Jones!

February 8, 2025

Comedian Aidan Jones (@aidanjonescomedy) joins Matt, Andy and Jesse to talk about his musical comedy show Chopin's Nocturne, returning to classical music after a long break, piano tuning dorkery, doing Mozart covers, 66 million-year-old fish vomit, racy Mozart compositions, drawing dinosaurs with Zhao Chuang, talking dinosaurs with same and jerking it during a volcanic eruption.

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Episode 558 with Alice Fraser!

January 24, 2025

Comedian Alice Fraser (@aliterative) returns to the show to talk with Jesse, Andy and Matt about Jesse's mistimed melatonin, Alice's new book A Passion for Passion: A Delirious Love Letter to Romance, Hot Frosty, Matt's upcoming Australia shows, how ants can beat humans at cooperation, increasingly dumb reality dating shows, Andy's Naked Attraction obsession, science lectures on Pornhub, burial site clues to ancient British matriarchies and the first-ever audio and video of a meteorite's impact.

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Episode 557 with Mary Lynn Rajskub!

January 15, 2025

(Note: This episode was recorded before the Los Angeles fires) Comedian/actor Mary Lynn Rajskub (@marylynnrajskub) joins Jesse, Andy and Matt to talk about filming her upcoming show North of North in Nunavut, her new standup special Road Gig, how Roman air pollution lowered the IQ of Europe, long eggs, the thick ice of Europa, Matt's upcoming Australia shows and Andy's upcoming Arizona ones.

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Episode 556 with Laura Hayden!

January 7, 2025

Comedian and physical therapist Laura Hayden (@LauraHaydenFun) joins Jesse, Andy and Matt to talk about her penile pictorial book What About Dick, a decrease in average body temperature, sciatica advice, the benefits of pooping before you exercise, Matt's upcoming Australia tour and Andy's upcoming Warsaw Poland Bros gigs.

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Episode 555 with Forrest Shaw!

December 26, 2024

Comedian Forrest Shaw (@forrestshaw) returns to the show to talk about stalking manatees with police helicopters, gambling addiction, his upcoming podcast I've Got a Problem, survival of the wittiest, a lost branch of humanity's family tree, Matt's upcoming comedy shows in Eureka and Medford and Andy's upcoming Warsaw Poland Bros shows in Santa Barbara and Los Olivos.

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Episode 554 with Matthew Broussard!

December 10, 2024

Comedian Matthew Broussard (@mondaypunday) returns to the show to chat with Jesse, Andy and Matt about Matthew's new special Hyperbolic, exaggerated accents, the CEO shooter, cyborg beetles, a quantum computing milestone, gray goo, online security in a post-quantum world, elliptic curves, conic sections, Fermat's Enigma and a super old bird mother.

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Episode 553 with Becky Braunstein!

December 7, 2024

Comedian Becky Braunstein (@beckyfromalaska) joins Andy, Jesse and Matt to talk about growing up Jewish in Alaska, eruv rules and topology, orcas bringing back the salmon hat fad, the dangers of squeezing limes in bright sunlight, and tiny vodka-propelled robots.

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Episode 552 with Laura Kightlinger!

November 29, 2024

Comedian/writer/actress Laura Kightlinger (@KingKightlinger) joins Matt, Jesse and Andy to talk about spontaneous human combustion, Bourbon Room comedy shows in Hollywood, the story behind Andy's various bands, the Uranus story we don't want to cover, how one atom can change a parrot's color, blurb machine Peter Travers, peacock spiders, a blue whale that's been leaking oil for 26 years and a flu strain that we've basically beaten.

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Episode 551 with James Lamont!

November 19, 2024

Screenwriter James Lamont joins Matt, Jesse and Andy to talk about writing the upcoming Paddington in Peru, alcohol detox champion hornets, Shatner's double SPATS, memory not being confined to the brain, Jesse getting checked in on by local kids and Matt's oath to take up arms for the United States.

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Episode 550 with Benny Blue!

November 7, 2024

Comedian Benny Blue (@bennyblueeyes) joins Jesse, Andy and Matt to talk about brat summer transitioning into the fall of civilization, Benny's new special Live From My Mother's Funeral, Benny and Andy's Blue Lake connection, Anarchist Cookbook adolescent shenanigans, why humans are the perfect size for speed, Matt and Andy's show with the 2022-iest name ever, the best mural ever painted and its painter, Norm MacDonald's sketch artist sketch, how an asteroid got ants into farming fungi, Jesse's love of 90-Day Fiancee, Matt's upcoming comedy shows and Andy's upcoming ska shows.

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Episode 549 with Brooks Wheelan!

November 2, 2024

Comedian and former Probably Science cohost Brooks Wheelan (@brookswheelan) joins Jesse and Andy to talk about his new special Alive In Alaska, Tony Hinchcliffe entering the election arena, cats beating babies at word association, Don't Wake Daddy, snake talk just for Brooks, the Teddy Roosevelt biography The River of Doubt, Chuck Klosterman's The Nineties, the ever-changing landscape of standup and Andy's upcoming gigs with Warsaw Poland Bros.

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Episode 548 with Jeffrey Jay!

October 18, 2024

Comedian Jeffrey Jay (@heyjeffreyjay) joins Matt, Jesse and Andy to discuss UnCertified Fresh, the Matt Walsh-iverse of awful movies, Earth gaining a second moon, the orbital path of that object, an octopus that punches fish to make them help it hunt and choceted EEG caps for cats.

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Episode 547 with DJ Qualls and Kelly Blackheart!

October 10, 2024

DJ Qualls (@TheOnlyDJQualls) and Kelly Blackheart (@kellyblackheart) of the Locked & Probably Loaded podcast join Matt and Jesse to talk about DJ's upcoming movie Carved, Nashville dive bars, the Ark Encounter, the Ig Nobel prize for butt-breathing, extreme aging, re-creating Mars in a lab and resurrecting the woolly mammoth.

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